Human iNKT Cells Promote Protective Inflammation by Inducing Oscillating Purinergic Signaling in Monocyte-Derived DCs

Invariant natural killer T (iNKT) cells are innate T lymphocytes that promote host defense against a variety of microbial pathogens. Whether microbial ligands are required for their protective effects remains unclear. Here, we show that iNKT cells stimulate human-monocyte-derived dendritic cells (DC...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Xu, Xuequn, Pocock, Ginger M., Sharma, Akshat, Peery, Stephen L., Fites, J. Scott, Felley, Laura, Zarnowski, Robert, Stewart, Douglas, Berthier, Erwin, Klein, Bruce S., Sherer, Nathan M., Gumperz, Jenny E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043518/
https://ncbi.nlm.nih.gov/pubmed/27653689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.061
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