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Chemical and neuropathological analyses of an Alzheimer’s disease patient treated with solanezumab

Introduction: Based on the amyloid cascade hypothesis of Alzheimer’s disease (AD) pathogenesis, a series of clinical trials involving immunotherapies have been undertaken including infusion with the IgG1 monoclonal anti-Aβ antibody solanezumab directed against the middle of the soluble Aβ peptide. I...

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Veröffentlicht in:Am J Neurodegener Dis
Hauptverfasser: Roher, Alex E, Maarouf, Chera L, Kokjohn, Tyler A, Belden, Christine, Serrano, Geidy, Sabbagh, Marwan S, Beach, Thomas G
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043095/
https://ncbi.nlm.nih.gov/pubmed/27725918
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