Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme.

Ribozymes are RNAs that possess the dual properties of RNA sequence-specific recognition, analogous to conventional antisense molecules, and RNA substrate destruction via site-specific cleavage. The cleavage reaction is catalytic in that more than one substrate molecule is processed per ribozyme mol...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Ojwang, J O, Hampel, A, Looney, D J, Wong-Staal, F, Rappaport, J
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1992
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10802
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