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Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme.

Ribozymes are RNAs that possess the dual properties of RNA sequence-specific recognition, analogous to conventional antisense molecules, and RNA substrate destruction via site-specific cleavage. The cleavage reaction is catalytic in that more than one substrate molecule is processed per ribozyme mol...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ojwang, J O, Hampel, A, Looney, D J, Wong-Staal, F, Rappaport, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438280/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10802
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