Long Non-coding RNA HOTAIR Expression in Diffuse Large B-Cell Lymphoma: In Relation to Polycomb Repressive Complex Pathway Proteins and H3K27 Trimethylation

BACKGROUND: A long non-coding RNA hox transcript antisense intergenic RNA (HOTAIR) is involved in epigenetic regulation through chromatin remodeling by recruiting polycomb repressive complex 2 (PRC2) proteins (EZH2, SUZ12, and EED) that induce histone H3 trimethylation at lysine 27 (H3K27me3). Dereg...

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Veröffentlicht in:J Pathol Transl Med
Hauptverfasser: Oh, Eun Ji, Kim, Soo Hee, Yang, Woo Ick, Ko, Young Hyeh, Yoon, Sun Och
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Pathologists and the Korean Society for Cytopathology 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042898/
https://ncbi.nlm.nih.gov/pubmed/27550047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2016.06.06
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