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Fine Mapping Implicates a Deletion of CFHR1 and CFHR3 in Protection from IgA Nephropathy in Han Chinese

An intronic variant at the complement factor H (CFH) gene on chromosome 1q32 (rs6677604) associates with risk of IgA nephropathy (IgAN), but the association signal has not been uniformly replicated in Han Chinese populations. We investigated whether the causal sequence variant resides in the CFH gen...

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Bibliografische gegevens
Gepubliceerd in:J Am Soc Nephrol
Hoofdauteurs: Xie, Jingyuan, Kiryluk, Krzysztof, Li, Yifu, Mladkova, Nikol, Zhu, Li, Hou, Ping, Ren, Hong, Wang, Weiming, Zhang, Hong, Chen, Nan, Gharavi, Ali G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042673/
https://ncbi.nlm.nih.gov/pubmed/26940089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015111210
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