Fine Mapping Implicates a Deletion of CFHR1 and CFHR3 in Protection from IgA Nephropathy in Han Chinese

An intronic variant at the complement factor H (CFH) gene on chromosome 1q32 (rs6677604) associates with risk of IgA nephropathy (IgAN), but the association signal has not been uniformly replicated in Han Chinese populations. We investigated whether the causal sequence variant resides in the CFH gen...

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Udgivet i:J Am Soc Nephrol
Main Authors: Xie, Jingyuan, Kiryluk, Krzysztof, Li, Yifu, Mladkova, Nikol, Zhu, Li, Hou, Ping, Ren, Hong, Wang, Weiming, Zhang, Hong, Chen, Nan, Gharavi, Ali G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042673/
https://ncbi.nlm.nih.gov/pubmed/26940089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015111210
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