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Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort

Two common missense variants in APOL1 (G1 and G2) have been definitively linked to CKD in black Americans. However, not all individuals with the renal-risk genotype develop CKD, and little is known about how APOL1 variants drive disease. Given the association of APOL1 with HDL particles, which are c...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kozlitina, Julia, Zhou, Haihong, Brown, Patricia N., Rohm, Rory J., Pan, Yi, Ayanoglu, Gulesi, Du, Xiaoyan, Rimmer, Eric, Reilly, Dermot F., Roddy, Thomas P., Cully, Doris F., Vogt, Thomas F., Blom, Daniel, Hoek, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042671/
https://ncbi.nlm.nih.gov/pubmed/27005919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101121
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