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The biology of APOL1 with insights into the association of APOL1 variants with chronic kidney disease

Recent studies have identified genetic variants in APOL1 that may contribute to the increased incidence of kidney disease in populations with African ancestry. Herein, we review the biology of APOL1 present in the circulation and localized to the kidney as it may contribute to the pathogenesis of AP...

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Bibliografiske detaljer
Main Authors: Madhavan, Sethu, O'Toole, John F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022720/
https://ncbi.nlm.nih.gov/pubmed/24233469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-013-0907-4
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