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Single Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH(3)T(3) Cells
Synonymous mutations in the KRAS gene are clustered at G12, G13, and G60 in human cancers. We constructed 9 stable NIH(3)T(3) cell lines expressing KRAS, each with one of these synonymous mutations. Compared to the negative control cell line expressing the wild type human KRAS gene, all the synonymo...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042562/ https://ncbi.nlm.nih.gov/pubmed/27684555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163272 |
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