Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways

BACKGROUND: Benzo(a)pyrene (BaP), naphthalene (NPh), phenanthrene (Phe), benzo(a)antharacene (BeA), and benzo(b)fluoranthene (BeF) are known carcinogenic polyaryl hydrocarbons (PAHs) present in cigarette smoke. This study was designed to examine the relative effect of these constituents on the cytot...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ranjit, Sabina, Midde, Narasimha M., Sinha, Namita, Patters, Benjamin J., Rahman, Mohammad A., Cory, Theodore J., Rao, P. S. S., Kumar, Santosh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042547/
https://ncbi.nlm.nih.gov/pubmed/27684561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163827
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