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Specific packaging and circulation of cytochromes P450, especially 2E1 isozyme, in human plasma exosomes and their implications in cellular communications

Cytochrome P450 (CYP) enzymes metabolize the majority of xenobiotics and are mainly found in hepatic and some extra-hepatic cells. However, their presence and functional role in exosomes, small extracellular vesicles that are secreted from various cells into extracellular fluids including plasma, is...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Kumar, Santosh, Sinha, Namita, Gerth, Kelli A., Rahman, Mohammad A., Yallapu, Murali M., Midde, Narasimha M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901973/
https://ncbi.nlm.nih.gov/pubmed/28756226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.07.145
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