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SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
DNA ligases are attractive therapeutics because of their involvement in completing the repair of almost all types of DNA damage. A series of DNA ligase inhibitors with differing selectivity for the three human DNA ligases were identified using a structure-based approach with one of these inhibitors...
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| Опубликовано в: : | DNA Repair (Amst) |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042453/ https://ncbi.nlm.nih.gov/pubmed/27235626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.04.004 |
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