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Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-β

BACKGROUND & AIMS: Monocyte and macrophage (MΦ) activation contributes to the pathogenesis of chronic hepatitis C virus (HCV) infection. Disease pathogenesis is regulated by both liver-resident MΦs and monocytes recruited as precursors of MΦs into the damaged liver. Monocytes differentiate into...

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Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Saha, Banishree, Kodys, Karen, Szabo, Gyongyi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042356/
https://ncbi.nlm.nih.gov/pubmed/28090562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.12.005
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