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Krüppel‐like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease

Macrophages play an important role in inflammation and liver injury. In ALD, activated macrophages, including M1 (proinflammatory) and M2 (anti‐inflammatory) macrophages, are present in the liver. As KLF4 has been described as a regulator of macrophage polarization, we investigated its role in ALD....

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Détails bibliographiques
Publié dans:J Leukoc Biol
Auteurs principaux: Saha, Banishree, Bala, Shashi, Hosseini, Nooshin, Kodys, Karen, Szabo, Gyongyi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608000/
https://ncbi.nlm.nih.gov/pubmed/25740962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A1014-485R
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