Research Techniques Made Simple: The Application of CRISPR-Cas9 and Genome Editing in Investigative Dermatology

Designer nucleases have gained widespread attention for their ability to precisely modify genomic DNA in a programmable manner. These genome-editing nucleases make double-stranded breaks at specified loci, and desired changes can be made to modify, ablate, or excise target genes. This technology has...

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Bibliographic Details
Published in:J Invest Dermatol
Main Authors: Guitart, Joan Ramon, Johnson, Jodi L., Chien, Wade W.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042211/
https://ncbi.nlm.nih.gov/pubmed/27542298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.06.007
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