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New Vectors for Simple and Streamlined CRISPR-Cas9 Genome Editing in Saccharomyces cerevisiae

CRISPR-Cas9 technology is an important tool for genome editing because the Cas9 endonuclease can induce targeted DNA double-strand breaks. Targeting of the DNA break is typically controlled by a single-guide RNA (sgRNA) – a chimeric RNA containing a structural segment important for Cas9 binding and...

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Publicado en:Yeast
Main Authors: Laughery, Marian F., Hunter, Tierra, Brown, Alexander, Hoopes, James, Ostbye, Travis, Shumaker, Taven, Wyrick, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715497/
https://ncbi.nlm.nih.gov/pubmed/26305040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.3098
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