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Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles
B-Raf represents a critical physiological regulator of the Ras/RAF/MEK/ERK-pathway and a pharmacological target of growing clinical relevance, in particular in oncology. To understand how B-Raf itself is regulated, we combined mass spectrometry with genetic approaches to map its interactome in MCF-1...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042004/ https://ncbi.nlm.nih.gov/pubmed/27034005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8427 |
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