IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

Epigenetic alterations, including dysregulated DNA methylation and histone modifications, govern the progression of colorectal cancer (CRC). Cancer cells exploit epigenetic regulation to control cellular pathways, including apoptotic and metastatic signals. Since aberrations in epigenome can be phar...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Buoncervello, Maria, Romagnoli, Giulia, Buccarelli, Mariachiara, Fragale, Alessandra, Toschi, Elena, Parlato, Stefania, Lucchetti, Donatella, Macchia, Daniele, Spada, Massimo, Canini, Irene, Sanchez, Massimo, Falchi, Mario, Musella, Martina, Biffoni, Mauro, Belardelli, Filippo, Capone, Imerio, Sgambato, Alessandro, Vitiani, Lucia Ricci, Gabriele, Lucia
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041985/
https://ncbi.nlm.nih.gov/pubmed/27028869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8379
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