UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

Colorectal cancer (CRC) is one of the most common and lethal cancers worldwide. Despite recent progress, the prognosis of advanced stage CRC remains poor, mainly because of cancer recurrence and metastasis. The high morbidity and mortality of CRC has been recently ascribed to a small population of t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Signore, Michele, Buccarelli, Mariachiara, Pilozzi, Emanuela, De Luca, Gabriele, Cappellari, Marianna, Fanciulli, Maurizio, Goeman, Frauke, Melucci, Elisa, Biffoni, Mauro, Ricci-Vitiani, Lucia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190083/
https://ncbi.nlm.nih.gov/pubmed/27286453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9859
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