UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

Colorectal cancer (CRC) is one of the most common and lethal cancers worldwide. Despite recent progress, the prognosis of advanced stage CRC remains poor, mainly because of cancer recurrence and metastasis. The high morbidity and mortality of CRC has been recently ascribed to a small population of t...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Signore, Michele, Buccarelli, Mariachiara, Pilozzi, Emanuela, De Luca, Gabriele, Cappellari, Marianna, Fanciulli, Maurizio, Goeman, Frauke, Melucci, Elisa, Biffoni, Mauro, Ricci-Vitiani, Lucia
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190083/
https://ncbi.nlm.nih.gov/pubmed/27286453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9859
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