Chimeric Plant Virus Particles as Immunogens for Inducing Murine and Human Immune Responses against Human Immunodeficiency Virus Type 1

The high-yield expression of a neutralizing epitope from human immunodeficiency virus type 1 (HIV-1) on the surface of a plant virus and its immunogenicity are presented. The highly conserved ELDKWA epitope from glycoprotein (gp) 41 was expressed as an N-terminal translational fusion with the potato...

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Detalhes bibliográficos
Main Authors: Marusic, Carla, Rizza, Paola, Lattanzi, Laura, Mancini, Camillo, Spada, Massimo, Belardelli, Filippo, Benvenuto, Eugenio, Capone, Imerio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115088/
https://ncbi.nlm.nih.gov/pubmed/11507188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8434-8439.2001
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