Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis

Glioma-associated oncogene 2 (Gli2), a primary transcriptional regulator of Hedgehog (Hh) signaling, is essential for hepatocellular carcinoma (HCC) growth and survival. However, the underlying molecular mechanism and crucial downstream targets of Gli2 in human HCC are not fully understood. Here, we...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shi, Chao, Huang, Dengliang, Lu, Nonghua, Chen, Dan, Zhang, Minhong, Yan, Yehong, Deng, Libin, Lu, Quqin, Lu, Hua, Luo, Shiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041975/
https://ncbi.nlm.nih.gov/pubmed/27036048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8441
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