Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis

Glioma-associated oncogene 2 (Gli2), a primary transcriptional regulator of Hedgehog (Hh) signaling, is essential for hepatocellular carcinoma (HCC) growth and survival. However, the underlying molecular mechanism and crucial downstream targets of Gli2 in human HCC are not fully understood. Here, we...

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Pubblicato in:Oncotarget
Autori principali: Shi, Chao, Huang, Dengliang, Lu, Nonghua, Chen, Dan, Zhang, Minhong, Yan, Yehong, Deng, Libin, Lu, Quqin, Lu, Hua, Luo, Shiwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041975/
https://ncbi.nlm.nih.gov/pubmed/27036048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8441
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