Loss of HIF-1β in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

Activation of hypoxia-inducible factor (HIF) and macrophage infiltration of solid tumors independently promote tumor progression. As little is known how myeloid HIF affects tumor development, we injected the polycyclic aromatic hydrocarbon (PAH) and procarcinogen 3-methylcholanthrene (MCA; 100 μg/10...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Henke, Nina, Ferreirós, Nerea, Geisslinger, Gerd, Ding, Martina G., Essler, Silke, Fuhrmann, Dominik C., Geis, Theresa, Namgaladze, Dmitry, Dehne, Nathalie, Brüne, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041954/
https://ncbi.nlm.nih.gov/pubmed/27015123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8297
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