Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer

The JNK and P38α pathways play a crucial role in tissue homeostasis, apoptosis and autophagy under genotoxic stresses, but it is unclear whether single nucleotide polymorphisms (SNPs) of genes in these pathways play a role in platinum-based chemotherapy-induced toxicities in patients with advanced n...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jia, Ming, Zhu, Meiling, Wang, Mengyun, Sun, Menghong, Qian, Ji, Ding, Fei, Chang, Jianhua, Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041904/
https://ncbi.nlm.nih.gov/pubmed/26993769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8052
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