Genetic variants of DNA repair genes predict the survival of patients with esophageal squamous cell cancer receiving platinum-based adjuvant chemotherapy

BACKGROUND: Adjuvant chemotherapy in patients with resected esophageal squamous cell cancer (ESCC) remains controversial for its uncertain role in improving overall survival (OS). Nucleotide excision repair (NER) removes DNA-adducts in tumor cells induced by the platinum-based chemotherapy and thus...

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Foilsithe in:J Transl Med
Main Authors: Zhou, Fei, Zhu, Meiling, Wang, Mengyun, Qiu, Lixin, Cheng, Lei, Jia, Ming, Xiang, Jiaqing, Wei, Qingyi
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2016
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888614/
https://ncbi.nlm.nih.gov/pubmed/27246611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0903-z
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