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Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia
MLL rearrangements occur in myeloid and lymphoid leukemias and are generally associated with a poor prognosis, however this varies depending on the fusion partner. We modeled acute myeloid leukemia (AML) in mice using various MLL fusion proteins (MLL-FPs) and observed significantly different surviva...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041898/ https://ncbi.nlm.nih.gov/pubmed/27007052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8199 |
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