Lin(neg) Sca-1(high) CD49f(high) prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo

A cell line was established from ventral prostate (VP) tumors of one-year-old Hi-Myc mice. These cells, called HMVP2 cells, are Lin(neg)Sca-1(high)CD49f(high) with high CD44 and CD29 expression and express CK14, Sca-1 and CD49f (but not CK8), suggesting basal-epithelial characteristics. Furthermore,...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Saha, Achinto, Blando, Jorge, Fernandez, Irina, Kiguchi, Kaoru, DiGiovanni, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041897/
https://ncbi.nlm.nih.gov/pubmed/26910370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7535
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