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SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24(+) CD49f(hi) Mammary Stem Cell-Enriched Compartment

Estrogen stimulates breast development during puberty and mammary tumors in adulthood through estrogen receptor-α (ERα). These effects are proposed to occur via ERα(+) luminal cells and not the mammary stem cells (MaSCs) that are ERα(neg). Since ERα(+) luminal cells express stem cell antigen-1 (SCA-...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Dall, Genevieve V., Vieusseux, Jessica L., Korach, Kenneth S., Arao, Yukitomo, Hewitt, Sylvia C., Hamilton, Katherine J., Dzierzak, Elaine, Boon, Wah Chin, Simpson, Evan R., Ramsay, Robert G., Stein, Torsten, Morris, Joanne S., Anderson, Robin L., Risbridger, Gail P., Britt, Kara L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312257/
https://ncbi.nlm.nih.gov/pubmed/28132885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.022
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