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CD44(pos)CD49f(hi)CD133/2(hi) Defines Xenograft-Initiating Cells in Estrogen Receptor-Negative Breast Cancer

Defining the populations of tumor-initating cells that are present in tumors is a first step in developing therapeutics to target these cells. We show here that both CD44(pos)CD24(neg) and CD44(pos)CD24(pos) cell populations in estrogen receptor (ER) α–negative breast tumors are tumorigenic in murin...

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Detalhes bibliográficos
Main Authors: Meyer, Matthew J., Fleming, Jodie M., Lin, Amy F., Hussnain, S. Amal, Ginsburg, Erika, Vonderhaar, Barbara K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129519/
https://ncbi.nlm.nih.gov/pubmed/20484027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3619
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