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MMP-9 Induces CD44 Cleavage and CD44 mediated Cell Migration in Glioblastoma Xenograft Cells
CD44 is implicated in cell-cell and cell-matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic potential in various cancers. In this study, we demonstrate that matrix metalloproteinase-9 (MMP-9) acts as a processing enzyme for CD44 cleavage. Fu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481542/ https://ncbi.nlm.nih.gov/pubmed/22024282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.10.008 |
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