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Effect of Metformin, Rapamycin and Their Combination on Growth and Progression of Prostate Tumors in HiMyc Mice

In this study, we compared the effect of oral administration of metformin (MET) and rapamycin (RAPA) alone or in combination on prostate cancer (PCa) development and progression in HiMyc mice. MET (250 mg/kg body weight in the drinking water), RAPA (2.24 mg/kg body weight microencapsulated in the di...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Saha, Achinto, Blando, Jorge, Tremmel, Lisa, DiGiovanni, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491032/
https://ncbi.nlm.nih.gov/pubmed/25908508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0014
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