FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function

Forkhead box A1 (FOXA1) is an FKHD family protein that plays pioneering roles in lineage-specific enhancer activation and gene transcription. Through genome-wide location analyses, here we show that FOXA1 expression and occupancy are, in turn, required for the maintenance of these epigenetic signatu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yang, Yeqing A., Zhao, Jonathan C., Fong, Ka-wing, Kim, Jung, Li, Shangze, Song, Chunxiao, Song, Bing, Zheng, Bin, He, Chuan, Yu, Jindan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041455/
https://ncbi.nlm.nih.gov/pubmed/27257062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw498
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