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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function
Forkhead box A1 (FOXA1) is an FKHD family protein that plays pioneering roles in lineage-specific enhancer activation and gene transcription. Through genome-wide location analyses, here we show that FOXA1 expression and occupancy are, in turn, required for the maintenance of these epigenetic signatu...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041455/ https://ncbi.nlm.nih.gov/pubmed/27257062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw498 |
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