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Preferential extension of short telomeres induced by low extracellular pH

The majority of tumor cells overcome proliferative limit by expressing telomerase. Whether or not telomerase preferentially extends the shortest telomeres is still under debate. When human cancer cells are cultured at neutral pH, telomerase extends telomeres in telomere length-independent manner. Ho...

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Publicado en:Nucleic Acids Res
Autores principales: Ge, Yuanlong, Wu, Shu, Xue, Yong, Tao, Jun, Li, Feng, Chen, Yanlian, Liu, Haiying, Ma, Wenbin, Huang, Junjiu, Zhao, Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041450/
https://ncbi.nlm.nih.gov/pubmed/27220467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw464
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