Inhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritis

Osteoarthritis (OA) is a common debilitating joint disorder, there’s still no available disease-modifying drug for OA currently. This study aims to explore the role of TAK1 in OA pathogenesis and therapeutic efficiency of TAK1 inhibition for OA. The contribution of TAK1 to OA pathogenesis was invest...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Cheng, Jin, Hu, Xiaoqing, Dai, Linghui, Zhang, Xin, Ren, Bo, Shi, Weili, Liu, Zhenlong, Duan, Xiaoning, Zhang, Jiying, Fu, Xin, Chen, Wenqing, Ao, Yingfang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041103/
https://ncbi.nlm.nih.gov/pubmed/27682596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34497
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