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Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of Osteoarthritis

Osteoarthritis (OA) is a common, degenerative joint disease characterized by articular cartilage degradation. Currently, clinical trials based on microRNA therapy have been performed to treat various diseases. However, no treatment has been found for arthritis. This study investigated the functions...

詳細記述

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書誌詳細
出版年:Mol Ther
主要な著者: Dai, Linghui, Zhang, Xin, Hu, Xiaoqing, Liu, Qiang, Man, Zhentao, Huang, Hongjie, Meng, Qingyang, Zhou, Chunyan, Ao, Yingfang
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817865/
https://ncbi.nlm.nih.gov/pubmed/25921548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.61
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