Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of Osteoarthritis

Osteoarthritis (OA) is a common, degenerative joint disease characterized by articular cartilage degradation. Currently, clinical trials based on microRNA therapy have been performed to treat various diseases. However, no treatment has been found for arthritis. This study investigated the functions...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Dai, Linghui, Zhang, Xin, Hu, Xiaoqing, Liu, Qiang, Man, Zhentao, Huang, Hongjie, Meng, Qingyang, Zhou, Chunyan, Ao, Yingfang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817865/
https://ncbi.nlm.nih.gov/pubmed/25921548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.61
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