Inhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritis

Osteoarthritis (OA) is a common debilitating joint disorder, there’s still no available disease-modifying drug for OA currently. This study aims to explore the role of TAK1 in OA pathogenesis and therapeutic efficiency of TAK1 inhibition for OA. The contribution of TAK1 to OA pathogenesis was invest...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, Jin, Hu, Xiaoqing, Dai, Linghui, Zhang, Xin, Ren, Bo, Shi, Weili, Liu, Zhenlong, Duan, Xiaoning, Zhang, Jiying, Fu, Xin, Chen, Wenqing, Ao, Yingfang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041103/
https://ncbi.nlm.nih.gov/pubmed/27682596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34497
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