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How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson’s disease?

Animal models of Parkinson’s disease (PD) are important for understanding the mechanisms of the disease and can contribute to developing and validating novel therapeutics. Ideally, these models should replicate the cardinal features of PD, such as progressive neurodegeneration of catecholaminergic n...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Volpicelli-Daley, Laura A., Kirik, Deniz, Stoyka, Lindsay E., Standaert, David G., Harms, Ashley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040622/
https://ncbi.nlm.nih.gov/pubmed/27018978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13627
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