Arsenic inhibits mast cell degranulation via suppression of early tyrosine phosphorylation events

Exposure to arsenic (As) is a global health concern. We previously documented an inhibitory effect of inorganic arsenite on IgE- mediated degranulation of RBL-2H3 mast cells (Hutchinson et al., 2011). Mast cells are tissue-resident cells that are positioned at the host-environment interface, thereby...

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Udgivet i:J Appl Toxicol
Main Authors: Shim, Juyoung, Kennedy, Rachel H., Weatherly, Lisa M., Hutchinson, Lee M., Pelletier, Jonathan H., Hashmi, Hina N., Blais, Kayla, Velez, Alejandro, Gosse, Julie A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040607/
https://ncbi.nlm.nih.gov/pubmed/27018130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3300
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