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Three-dimensional study of Alzheimer's disease hallmarks using the iDISCO clearing method
Amyloidosis is a major problem in over one hundred diseases including Alzheimer's disease (AD). Using the iDISCO visualization method involving targeted molecular labeling, tissue clearing and light-sheet microscopy, we studied plaque formation in the intact AD mouse brain and up to twenty-seve...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5040352/ https://ncbi.nlm.nih.gov/pubmed/27425620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.060 |
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