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Three-dimensional study of Alzheimer's disease hallmarks using the iDISCO clearing method
Amyloidosis is a major problem in over one hundred diseases including Alzheimer's disease (AD). Using the iDISCO visualization method involving targeted molecular labeling, tissue clearing and light-sheet microscopy, we studied plaque formation in the intact AD mouse brain and up to twenty-seve...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5040352/ https://ncbi.nlm.nih.gov/pubmed/27425620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.060 |
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