Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

Pulmonary inflammation and bacterial colonization are central to the pathogenesis of chronic obstructive pulmonary disease (COPD). Defects in macrophage phagocytosis of both bacteria and apoptotic cells contribute to the COPD phenotype. Small molecule inhibitors with anti-inflammatory activity again...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Bewley, Martin A., Belchamber, Kylie B. R., Chana, Kirandeep K., Budd, Richard C., Donaldson, Gavin, Wedzicha, Jadwiga A., Brightling, Christopher E., Kilty, Iain, Donnelly, Louise E., Barnes, Peter J., Singh, Dave, Whyte, Moira K. B., Dockrell, David H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040258/
https://ncbi.nlm.nih.gov/pubmed/27680884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163139
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