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Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq
Motivation: The detection of subtle genomic allelic imbalance events has many potential applications. For example, identifying cancer-associated allelic imbalanced regions in low tumor-cellularity samples or in low-proportion tumor subclones can be used for early cancer detection, prognostic assessm...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039922/ https://ncbi.nlm.nih.gov/pubmed/27288500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw340 |
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