Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice

Long term pulmonary exposure to crystalline silica leads to silicosis that manifests progressive interstitial fibrosis, eventually leading to respiratory failure and death. Despite efforts to eliminate silicosis, clinical cases continue to occur in both developing and developed countries. The exact...

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Опубликовано в: :Theranostics
Главные авторы: Li, Chao, Du, Sitong, Lu, Yiping, Lu, Xiaowei, Liu, Fangwei, Chen, Ying, Weng, Dong, Chen, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039680/
https://ncbi.nlm.nih.gov/pubmed/27698940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16180
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