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Role of IL-10-producing regulatory B cells in modulating T-helper cell immune responses during silica-induced lung inflammation and fibrosis

Silicosis is characterized by chronic lung inflammation and fibrosis, which are seriously harmful to human health. Previous research demonstrated that uncontrolled T-helper (Th) cell immune responses were involved in the pathogenesis of silicosis. Lymphocytes also are reported to have important role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Fangwei, Dai, Wujing, Li, Chao, Lu, Xiaowei, Chen, Ying, Weng, Dong, Chen, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926212/
https://ncbi.nlm.nih.gov/pubmed/27354007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28911
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