Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1

Glucagon-like peptide-1 (GLP-1) is an intestinal-secreted incretin that increases cellular glucose up-take to decrease blood sugar. Recent studies, however, suggest that the function of GLP-1 is not only to decrease blood sugar, but also acts as a neurotrophic factor that plays a role in neuronal su...

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Опубликовано в: :Theranostics
Главные авторы: Yang, Jenq-Lin, Chen, Wei-Yu, Chen, Yin-Ping, Kuo, Chao-Ying, Chen, Shang-Der
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039677/
https://ncbi.nlm.nih.gov/pubmed/27698937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15993
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