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Insulin enhanced leptin-induced STAT3 signaling by inducing GRP78

Leptin, an adipocyte-derived hormone, centrally regulates energy homeostasis. Overlaps in the regulation of glucose and energy homeostasis have been reported between leptin and insulin. However, the effects of insulin on leptin’s actions in the central nervous system (CNS) have not yet been elucidat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thon, Mina, Hosoi, Toru, Ozawa, Koichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039638/
https://ncbi.nlm.nih.gov/pubmed/27677243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34312
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