Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc(+/1638N) Mice: Comparisons and Contrasts

Obesity is an established risk factor for colorectal cancer (CRC). Our previous study indicated that obesity increases activity of the pro-tumorigenic Wnt-signaling. Presently, we sought to further advance our understanding of the mechanisms by which obesity promotes CRC by examining associations be...

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Publicado en:J Cancer
Autores principales: Liu, Wei, Crott, Jimmy W., Lyu, Lin, Pfalzer, Anna C., Li, Jinchao, Choi, Sang-Woon, Yang, Yingke, Mason, Joel B., Liu, Zhenhua
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2016
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039360/
https://ncbi.nlm.nih.gov/pubmed/27698916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15792
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