Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc(1638N) Mice

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on th...

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Publié dans:PLoS One
Auteurs principaux: Pfalzer, Anna C., Nesbeth, Paula-Dene C., Parnell, Laurence D., Iyer, Lakshmanan K., Liu, Zhenhua, Kane, Anne V., Chen, C-Y. Oliver, Tai, Albert K., Bowman, Thomas A., Obin, Martin S., Mason, Joel B., Greenberg, Andrew S., Choi, Sang-Woon, Selhub, Jacob, Paul, Ligi, Crott, Jimmy W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540493/
https://ncbi.nlm.nih.gov/pubmed/26284788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135758
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