Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc(1638N) Mice

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on th...

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Pubblicato in:PLoS One
Autori principali: Pfalzer, Anna C., Nesbeth, Paula-Dene C., Parnell, Laurence D., Iyer, Lakshmanan K., Liu, Zhenhua, Kane, Anne V., Chen, C-Y. Oliver, Tai, Albert K., Bowman, Thomas A., Obin, Martin S., Mason, Joel B., Greenberg, Andrew S., Choi, Sang-Woon, Selhub, Jacob, Paul, Ligi, Crott, Jimmy W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540493/
https://ncbi.nlm.nih.gov/pubmed/26284788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135758
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