Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.

The beta-globin locus control region (LCR) is characterized by erythroid-specific DNase I hypersensitive sites and is involved in the chromatin organization, transcriptional potentiation, developmental regulation, and replication timing of the entire beta-globin gene cluster. When and how the LCR is...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jiménez, G, Griffiths, S D, Ford, A M, Greaves, M F, Enver, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50392/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10618
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