Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.
The beta-globin locus control region (LCR) is characterized by erythroid-specific DNase I hypersensitive sites and is involved in the chromatin organization, transcriptional potentiation, developmental regulation, and replication timing of the entire beta-globin gene cluster. When and how the LCR is...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50392/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10618 |
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